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Lee, Youngsook, Ph.D.
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Professor Department of Life Science Division
of Molecular and Life Sciences Plant
Cell Biology
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Publications
Abstract E-mail ylee@postech.ac.kr
Phone +82-54-279-2296(office) +82-54-279-5980(lab.) Laboratory
Lab.
of the Plant Cell Biology
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Profile
| Research Interests
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Publications
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Profile
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1988 1988-1990
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Ph.D.,
University of Connecticut, Storrs,
CT, USA Postdoctoral Fellow, Harvard
University
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TOP
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Research Interests
Plant Cell Biology Laboratory
We
have two aims of research. First is to understand
the mechanisms of transport and detoxification of
the pollutants such as heavy metals and herbicides
by plants. The knowledge obtained from this project
can be used for development of plants that can be
useful for phytoremediation or safe crops that do
not absorb pollutants. Second is to understand
how plant cells sense and respond to various internal
and external changes such as light, water stress,
pollutants and herbivores. We identify the components
of the signal transduction pathways that lead to
stomatal movements and plant defense responses,
and investigate how they interact. The knowledge
obtained from this project can be used for development
of plants that are tolerant to drought, pathogen,
and other stresses, or those that can respond rapidly
and efficiently to physiological signals to open
or close stomata, thus optimizing photosynthesis
and water use efficiency. We
use molecular biological techniques, immunolocalization,
as well as electrophysiological techniques. For
example, patch clamping technique is powerful in
providing information on the activities of individual
ion transporters. We also use expression systems
such as Xenopus oocytes to identify the functionss
of plant transporter genes.
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Selected Publications
- Miyoung Lee, Yongwook Choi, Yu-Young Kim, Byeongwook Jeon, Bo Burla, Masayoshi Maeshima, Joo-Yeon Yoo, Enrico Martinoia and Youngsook Lee, 2008. The ABC transporter AtPGP14 is a malate importer and modulates stomatal response to CO2. Nature Cell Biology 10: 1217-23
- Donghwan Shim, Jae-Ung Hwang, Joohyun Lee, Sichul Lee, Gynheung An, Enrico Martinoia and Youngsook Lee (2009) Orthologs of the class A4 heat shock transcription factor HsfA4a confer Cadmium tolerance in wheat and rice. The Plant Cell. 21:4031-43.
- Joohyun Kang, Jae-Ung Hwang, Miyoung Lee, Enrico Martinoia and Youngsook Lee (2010) A PDR-type ABC transporter mediates cellular uptake of the phytohormone abscisic acid. PNAS USA 107: 2355-2360
- Won-Yong Song, Kwan Sam Choi, Do Young Kim, Markus Geisler, Jiyoung Park, Vincent Vincenzetti, Maja Schellenberg, Sun Ha Kim, Yong Pyo Lim, Eun Woon Noh, Youngsook Lee*, Martinoia E.* (2010) Arabidopsis PCR2 is a Zinc exporter involved in both Zinc extrusion and long-distance Zinc transport. The Plant Cell, 22: 2237-2252 *equal contribution
- Won-Yong Song, Jiyoung Park, David G. Mendoza-Cózatl, Marianne Suter-Grotemeyer, Donghwan Shim, Stefan Hörtensteiner, Markus Geisler, Barbara Weder, Philip A. Rea, Doris Rentsch, Julian I. Schroeder*, Youngsook Lee*, Enrico Martinoia* (2010) Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters. PNAS, USA, 107: 21187-92. *equal contribution
- Hyunju Choi, Jun-Young Jin, Setbyoul Choi, Jae-Ung Hwang, Yu-Young Kim, Mi Chung Suh and Youngsook Lee (2011) An ABCG/WBC-type ABC transporter is essential for transport of sporopollenin precursors for exine formation in developing pollen. The Plant Journal, 65:181-93
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Division
of Molecular & Life Sciences| POSTECH |
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