Functional Proteomics

We are trying to predict human proteins secreted to the extracellular space by using bioinformatics approaches and to systematically investigate the functions of the secretory proteins by using a novel yeast genetic system named zymogand through co-cultivation of yeast and human cells.

  1. Prediction of secretory proteins.
  2. Development of a genetic system (zymogand) suitable for analyzing functions of secretory protein at the proteome level.
  3. Determination of functions of human secretory proteins.

Zymogand system

Zymogand system suitable for determining functions of human gene products by co-cultivation of human and yeasts without purification of proteins