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Profile.
Name	Jongbong Lee
Organization	Dept of Physics
Telephone	279-2095
E-mail	jblee@postech.ac.kr
Homepage	http://jblab.postech.ac.kr

Journal Papers

International

Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formation, Nature Communications, , 11, - (2020)
DNA Mismatch Repair Relies Entirely on Stochastic Transactions, Biophysical Journal, , 116, 73A-74A (2019)
Muts Homolog Sliding Clamps Shield the DNA from Binding Proteins, BIOPHYSICAL JOURNAL, , 116, 75A-75A (2019)
Multiplexed single-molecule flow-stretching bead assay for DNA enzymology, BMB REPORTS, , 52, 589-594 (2019)
Single-molecule DNA flow-stretching force spectroscopy with higher resolution using dark-field microscopy., Journal of the Korean Physical Society, , 75, 350-354 (2019)
DNA skybridge: 3D structure producing a light sheet for high-throughput single-molecule imaging, NUCLEIC ACIDS RESEARCH, , 47, e107- (2019)
MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair, NATURE COMMUNICATIONS, , 10, - (2019)
Dynamics of Proofreading by the E. coli Pol III Replicase, Cell Chemical Biology, , 25, 57-66 (2018)
MutS homolog sliding clamps shield the DNA from binding proteins, JOURNAL OF BIOLOGICAL CHEMISTRY, , 293, 14285-14294 (2018)
Coordinating Multi-Protein Mismatch Repair by Managing Diffusion Mechanics on the DNA, JOURNAL OF MOLECULAR BIOLOGY, , 430, 4469-4480 (2018)
Stochastic Processes and Component Plasticity Governing DNA Mismatch Repair, JOURNAL OF MOLECULAR BIOLOGY, , 430, 4456-4468 (2018)
The bent conformation of poly(A)-binding protein induced by RNA-binding is required for its translational activation function, RNA biology, , 14, 370-377 (2017)
Extended depth of field for single biomolecule optical imaging-force spectroscopy, OPTICS EXPRESS, , 25, 32189-32197 (2017)
Light-Induced Fluorescence Modulation of Quantum Dot-Crystal Violet Conjugates: Stochastic Off–On–Off Cycles for Multicolor Patterning and Super-Resolution, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, , 139, 7603-7615 (2017)
Dynamic control of strand excision during human DNA mismatch repair, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 113, 3281-3286 (2016)
Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting, Nature communications, , 7, 11107- (2016)
Retroviral intasomes search for a target DNA by 1D diffusion which rarely results in integration, Nature communications, , 7, - (2016)
Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair, NATURE, , 539, 583-+ (2016)
Analysis of Interactions between the Epidermal Growth Factor Receptor and Soluble Ligands on the Basis of Single-Molecule Diffusivity in the Membrane of Living Cells, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, , 54, 7028-7032 (2015)
An Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore, SCIENTIFIC REPORTS, , 5, - (2015)
Widespread nuclease contamination in commonly used oxygen-scavenging systems, NATURE METHODS, , 12, 901-902 (2015)
Interplay MutS with beta Clamp on Mismatched DNA, BIOPHYSICAL JOURNAL, , 108, 69A-69A (2015)
Poly(A) RNA and Paip2 act as allosteric regulators of poly(A)-binding protein, NUCLEIC ACIDS RESEARCH, , 42, 2697-2707 (2014)
Aptamer-based single-molecule imaging of insulin receptors in living cells, JOURNAL OF BIOMEDICAL OPTICS, , 19, - (2014)
Loading Dynamics of a sliding DNA clamp, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, , 53, 6768-6771 (2014)
Single-molecule views of MutS on mismatched DNA, DNA REPAIR, , 20, 82-93 (2014)
Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substrates, EMBO JOURNAL, , 33, 1061-1072 (2014)
Mapping of Surface-immobilized DNA with Force-based Atomic Force Microscopy, ANALYTICAL CHEMISTRY, , 85, 4045-4050 (2013)
Polarization-Controlled Photoswitching Resolves Dipole Directions with Subwavelength Resolution, physical review letters, , , - (2012)
Assessment of radiation damage in single-shot coherent diffraction of DNA molecules by an extreme-ultraviolet free-electron laser, Physical review E, , 86, - (2012)
ATP Alters the Diffusion Mechanics of MutS on Mismatched DNA, Structure, , 20, 1264-1274 (2012)
Unique Temperature Dependence and Blinking Behavior of CdTe/CdSe (Core/Shell) Type-II Quantum Dots, JOURNAL OF PHYSICAL CHEMISTRY C, , 115, 436-442 (2011)
MutS switches between two fundamentally distinct clamps during mismatch repair, NATURE STRUCTURAL AND MOLECULAR BIOLOGY, , 18, 379-U174 (2011)
Single-Molecule Analysis Reveals the Kinetics and Physiological Relevance of MutL-ssDNA Binding, PLOS ONE, , 5, - (2010)
Dynamic DNA helicase-DNA polymerase interactions assure processive replication fork movement, MOLECULAR CELL, , 27, 539-549 (2007)
DYNAMICS OF THE MOLECULAR ORIENTATION FIELD COUPLED TO IONS IN TWO-DIMENSIONAL FERROELECTRIC LIQUID CRYSTALS, PHYSICAL REVIEW E, , 76, - (2007)
Role of electrostatics in the texture of islands in free-standing ferroelectric liquid crystal films, PHYSICAL REVIEW E, , 75, - (2007)
DNA primase acts as a molecular brake in DNA replication, NATURE, , 439, 621-624 (2006)
TEXTURAL TRANSFORMATIONS IN ISLANDS ON FREE STANDING SMECTIC-C-* LIQUID CRYSTAL FILMS, PHYSICAL REVIEW E, , 73, - (2006)
Equilibrium size and textures of islands in free standing Smectic C* films., MOLECULAR CRYSTALS AND LIQUID CRYSTALS, , 364, 123-131 (2001)
Effect of the external twist on molecular orientation in antiferroelectric liquid crystals., MOLECULAR CRYSTALS AND LIQUID CRYSTALS SCIENCE AND TECHNOLOGY SECTION A-MOLECULAR CRYSTALS AND LIQUID CRYSTALS, , 301, 209- (1997)

Domestic Journal Papers

General Journal Papers

Single-molecule FRET Studies on DNA Mismatch Repair, International Journal of Biophysics, , 3, 18-38 (2013)

Conference Proceedings

The formation conditions of intercellular nanotube: A Critical rule of torque and restorative force, 2019년 가을 한국물리학회, 0, 0, - (2019)
The mechanism of formation of the intercellular nanotubes: Langevin dynamics simulation on the interwound filopodia, 2019년 봄 한국물리학회, 0, 0, - (2019)
Single-molecule analysis of PCNA-p15 interaction on DNA, KIAS Conference on Protein Structure and Function, 0, 0, - (2018)
Twisting of filopodia stiffens filopodial bridges for intercellular nanotube formation, 2018 한국물리학회 가을학술논문발표회, 0, 0, - (2018)
A correlative single-molecule technique, 2018년 한국물리학회 가을 학술논문발표회, 0, 0, - (2018)
A DNA substrate for studying DNA repair in a single cell, 2018년 한국물리학회 가을 학술논문발표회, 0, 0, - (2018)
Single-molecule analysis of DNA polymerases on lesion DNA, 2018년 한국물리학회 봄 학술논문발표회, 0, 0, - (2018)
Super-Resolution Imaging of Intercellular Nanotubes, 2018년 한국물리학회 봄 학술논문발표회, 0, 0, - (2018)
Single-molecule diffusion analysis of proteins on DNA, 2018년 한국물리학회 봄 학술논문발표회, 0, 0, - (2018)
Biophysical Studies on Intercellular Nanotubes in Living Cells, 2018 봄 학술논문발표회, 0, 0, - (2018)
Single-molecule Force-Fluorescense Spectroscopy in Expanded Focal Depth, 2017 한국물리학회 가을 학술논문발표회, 0, 0, - (2017)
Diffusion analysis of PCNA interacting with p15PAF on DNA, 2017 한국물리학회 가을 학술논문발표, 0, 0, - (2017)
Roadblock elimination by 1D Diffusion of DNA sliding clamps on DNA, 2017 한국물리학회 가을 학술논문발표회, 0, 0, - (2017)
Single-molecule Mechanistic Studies on DNA Proofreading by DNA Polymerase, 2017 한국물리학회 가을 학술논문발표회, 0, 0, - (2017)
Super-Resolved Nanostructure of Intercellular Nanotubes, 2016 한국물리학회 가을 학술논문발표회, 0, 0, - (2016)
The Measurement of Force exerted by DNA sliding clamps, 2016 한국물리학회 가을 학술논문발표회, 0, 0, - (2016)
Fluorescence imaging of the transition of dsDNA to ssDNA, 2016 한국물리학회 가을 학술논문발표회, 0, 0, - (2016)
Single Molecule Studies of Human Exonuclease 1, 2016 한국물리학회 봄 학술논문발표회, 0, 0, - (2016)
Diffusion analysis of PCNA interacting with p15PAF on DNA, 2016 한국물리학회 봄 학술논문발표회, 0, 0, - (2016)
Single-molecule Study of Intercellular EGFR Transport on Cellular Nanotubes, 2015 가을 학술회논문발표집, 0, 0, - (2015)
Single-Molecule studies on the Mechanism of mis-synthesized DNA strand removal in Human, 2015 가을 학술논문발표회, 0, 0, - (2015)
Interplay Muts, beta clamp and MutL on Mismatched DNA, 2015 가을 학술논문발표집, 0, 0, - (2015)
Single-molecule assay for UvrD helicase activity, 2015 봄 학술논문발표집, 0, 0, - (2015)
Single-Molecule Force-Fluorescence Spectroscopy in Living Cell, 2015 봄 학술논문발표논문집, 0, 0, - (2015)
Single-molecule studies of the ssDNA binding activity of E. coli MutL, 54TH BIOPHYSICAL SOCIETY ANNUAL MEETING, 0, 0, - (2010)

Invited Talk or Presentations

Langevin dynamics simulation of the mechanism of the intercellular nanotube, 2019 International Conference on Molecular Simulation, 0, 0, - (2019)
How Cells Kiss?, Statistical Physics for Biological Matter, 0, 0, - (2018)
Langevin dynamics simulation on the two interwound filopodia in the process of intercellular nanotube formation, 2018년 추계 한국물리학회, 0, 0, - (2018)
Twisting of filopodia stiffens filopodial bridges for intercellular nanotube formation, 2018년 추계 한국물리학회, 0, 0, - (2018)
Formation mechanics of intercellular nanotubes, 2018 GOEDON RESEARCH CONFERENCE, 0, 0, - (2018)
Alternative structures of PABP determine functions of the protein by changing interacting partners, ., 0, 0, - (2017)
Single-Molecule Approaches to Membrane Nanotubes, ., 0, 0, - (2016)
Interplay MutS with β clamp on Mismatched DNA, ., 0, 0, - (2015)
Single-molecule Study on the Proofreading activity of DNA Polymerase III, ., 0, 0, - (2014)
Removal Process of Mismatched Nucleotides during DNA Mismatch Repair, ., 0, 0, - (2014)
Diffusion Mechanics of the MutS and β clamp complex on Mismatched DNA, ., 0, 0, - (2014)
Loading Dynamics of DNA Replication Sliding-clamp, ., 0, 0, - (2014)
Single Molecule Studies on the Human DNA Mismatch Removal, ., 0, 0, - (2013)
Visualizing Conformational Changes and Diffusion Dynamics of DNA Replication Holoenzyme Beta-sliding clamp, ., 0, 0, - (2013)
ATP Alters the Diffusion Mechanics of MutS on Mismatched DNA, ., 0, 0, - (2012)
Superresolution and molecular orientation achieved by polarization-rotating TIRF microscopy, ., 0, 0, - (2012)
Dynamics of the Signaling MutS during Mismatch Repair, ., 0, 0, - (2012)
Poly(A) Binding Protein Tightly Bound to Poly(A): Its bent conformation and Dissociation Mechanism by Paip2, ., 0, 0, - (2012)
A simple flow-stretching method for a higher spatial resolution, ., 0, 0, - (2011)
Orientation and Rotational Diffusion of MutS during mismatch Repair, ., 0, 0, - (2011)
SINGLE-MOLECULE STUDY OF HUMAN POLY(A)-BINDING, ., 0, 0, - (2011)
DISTINCT CONFORMATIONAL CHANGES OF MUTS DURING, ., 0, 0, - (2011)
Direct observation of the dynamics of Taq MutS on mismatched DNA, ., 0, 0, - (2010)
Real-time Observation of Cytokine Signaling Proteins in Living Cells, ., 0, 0, - (2009)
DNA mismatch repair at the single-molecule level, ., 0, 0, - (2009)

Books

DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology, Springer, 35, 이종봉(책임) (2016)

Research Activities

DNA REPAIR MECHANISMS USING NOVEL SINGLE-MOECULE TECHNIQUES, 포항공과대학교 (2007-2008)
SINGLE-MOLECULE 수준에서 본 HELICASE에 의한 DNA 풀림의 메카니즘, 포항공과대학교 (2007-2007)
SINGLE-MOLECULE VIEW IN DNA REPAIR, 포항공과대학교 (2007-2008)
SINGLE-MOLECULE TECHNIQUES REVEAL HOW RIBOSOME 40S SEARCHES AUG CODON FOR TRANSLATION INITIATION, 한국학술진흥재단 (2007-2008)
당일분자 수준에서 DNA MISMATCH 복구 기작 연구, 포항공과대학교 (2008-2009)
DNA MISMATCH REPAIR AT THE SINGLE-MOLECULE LEVEL, 한국과학재단 (2008-2009)
EIF4G-EIF4A COMPLEX IN TRANSLATION INITIATION AT THE SINGLE-MOLECULE LEVEL, 한국학술진흥재단 (2008-2009)
형광편광을 이용한 공간 초고해상도 및 방향성 결정 현미경 개발, 포항공과대학교 (2009-2010)
생명물리 겨울 학교, 포항공과대학교 (2009-2010)
학생인건비통합관리과제, 포항공대산학협력단 (2009-2040)
DNA MISMATCH REPAIR AT THE SINGLE-MOLECULE LEVEL, 재단법인한국연구재단 (2009-2010)
세포막 단백질의 정량적인 역학 분석, 포항공과대학교 (2009-2010)
DNA 생체효소의 회전확산 연구(학부생연구프로그램), 포항공과대학교 (2009-2010)
EIF4G-EIF4A COMPLEX IN TRANSLATION INITIATION AT THE SINGLE-MOLECULE LEVEL, 재단법인한국연구재단 (2009-2010)
4.3208_2차년도 이월과제, 재단법인한국연구재단 (2009-2010)
4.3350 이월과제, 재단법인한국연구재단 (2009-2010)
DNA-PROTEIN INTERACTION AT THE SINGLE-MOLECULE LEVEL, 삼성전자(주) (2010-2010)
APPLICATION OF THE SINGLE-MOLECULE FRET USING ZEROMODE WAVEGUIDE, (재)한국과학창의재단 (2010-2011)
DNA MISMATCH REPAIR AT THE SINGLE-MOLECULE LEVEL, 재단법인한국연구재단 (2010-2011)
4.4624/4792_3차년도 이월과제, 재단법인한국연구재단 (2010-2011)
인건비풀링과제, 포항공대산학협력단 (2010-2015)
연구개발과제, 포항공대산학협력단 (2010-2016)
DNA METABOLISM IN CELL ENVIRONMENTS USING SINGLE-MOLECULE TECHNIQUES, 재단법인한국연구재단 (2011-2012)
정년보장심사대상 교원 기자재구입비 추가지원, 포항공과대학교 (2011-2012)
단일분자 관측을 위한 ZERO-MODE 도파관, 포항공대산학협력단 (2011-2012)
전반사에 의해 발생된 소실파를 이용한 생체분자 이미징, 경북교육청 (2012-2012)
DNA METABOLISM IN CELL ENVIRONMENT USING SINGLE-MOLECULE TECHNIQUES, 재단법인한국연구재단 (2012-2013)
4.6732_1차년도 이월과제, 재단법인한국연구재단 (2012-2013)
MULTIPLEXED FLOW-STRETCHING SINGLE-MOLECULE ASSAY, 포항공대산학협력단 (2013-2013)
생물물리 및 복잡계 연구 모임, 포항공과대학교 (2013-2014)
DNA METABOLISM IN CELL ENVIRONMENT USING SINGLE-MOLECULE TECHNIQUES, 재단법인한국연구재단 (2013-2014)
학부학생연구프로그램, 포항공과대학교 (2013-2013)
4.8232_2차년도 이월과제, 재단법인한국연구재단 (2013-2014)
DNA METABOLISM IN CELL ENVIRONMENT USING SINGLE-MOLECULE TECHNIQUES, 재단법인한국연구재단 (2014-2015)
4.9643의 이월과제, 재단법인한국연구재단 (2014-2015)
DNA METABOLISM IN CELL ENVIRONMENT USING SINGLE-MOLECULE TECHNIQUES, 재단법인한국연구재단 (2015-2016)
연구개발과제[2015년 신설], 포항공과대학교 (2015-2032)
[학부생연구프로그램]털의 온도측정잉크 염색 연구, 포항공과대학교 (2016-2016)
[BRSI-ISP]생명물리 연구모임, 포항공과대학교 (2016-2017)
단일분자 수준에서 손상된 DNA 합성 재구성, 포항공과대학교 (2016-2017)
MECHANISTIC STUDY OF LONG-DISTANCE COMMUNICATIONS ON DNA, 재단법인한국연구재단 (2016-2017)
BIOMOLECULES COMMUNICATION IN CELLS, 기초과학연구원 (2017-2017)
HUMAN DNA MISMATCH REPAIR: PRINCIPLES WITH APPLICATIONS FOR PRECISION MEDICINE, 재단법인한국연구재단 (2017-2018)
HUMAN DNA MISMATCH REPAIR: PRINCIPLES WITH APPLICATIONS FOR PRECISION MEDICINE, 재단법인한국연구재단 (2018-2019)
4.15023_이월과제, 재단법인한국연구재단 (2018-2019)
HUMAN DNA MISMATCH REPAIR: PRINCIPLES WITH APPLICATIONS FOR PRECISION MEDICINE, 재단법인한국연구재단 (2019-2020)
4.16756/15911 이월과제, 재단법인한국연구재단 (2019-2020)
HUMAN DNA MISMATCH REPAIR: PRINCIPLES WITH APPLICATIONS FOR PRECISION MEDICINE, 재단법인한국연구재단 (2020-2021)
CRYO-SINGLE-MOLECULE FLUORESCENCE IMAGING OF TRANSLATION INITIATION COMPLEXES IN CELLS, 재단법인한국연구재단 (2020-2021)
CRYO-SINGLE-MOLECULE FLUORESCENCE IMAGING OF TRANSLATION INITIATION COMPLEXES IN CELLS, 재단법인한국연구재단 (2021-2022)
HUMAN DNA MISMATCH REPAIR: PRINCIPLES WITH APPLICATIONS FOR PRECISION MEDICINE, 재단법인한국연구재단 (2021-2022)
4.0019366_이월과제, 재단법인한국연구재단 (2021-2022)
CRYO-SINGLE-MOLECULE FLUORESCENCE IMAGING OF TRANSLATION INITIATION COMPLEXES IN CELLS, 재단법인한국연구재단 (2022-2023)
HUMAN DNA MISMATCH REPAIR: PRINCIPLES WITH APPLICATIONS FOR PRECISION MEDICINE, 재단법인한국연구재단 (2022-2023)
4.0021479_이월과제, 재단법인한국연구재단 (2022-2023)
세포핵 생물물리 기초연구실, 재단법인한국연구재단 (2023-2024)
기초연구실지원사업 부서연구관리비, 포항공대산학협력단 (2023-2024)