POSTECH researchers have found another reason to cut down on a high-fat and cholesterol diet. Their findings show that cholesterol is crucial for Wnt signaling pathway often linked to human birth defects, cancer, and other diseases. Research groups of Prof. Jin-Kwan Han in the Department of Life Sciences at POSTECH and Prof. Wonhwa Cho from the University of Illinois at Chicago performed this study. Their research was published in the July edition of Nature Communications. Wnt signaling processes biological functions through ‘canonical’ and ‘non-canonical’ pathways..
The research team of Professors Jaesung Park (Department of Mechanical Engineering) and Yong Song Gho (Department of Life Sciences) has developed a way to generate artificial nanovesicles that can be used to deliver RNA, a breakthrough that is expected to be used in exosomes research and to have applications in drug and RNA-delivery systems. Their paper, "Microfluidicfabrication of cell-derived nanovesicles as endogenous RNA carriers”,made it onto the cover of the journalLab on a Chipand was selected as a Hot Article. Exosomes/microvesicles are known to shuttle biological signals..
Professor Sung H. Han (Department of Industrial and Management Engineering) is an authority in the field of ergonomics, an applied science that deals with the design of devices and systems in conjunction with the physical working conditions, capacities, and requirements of the user. Professor Han has conducted research on human-computer interaction,effectiveproduct design, and the evaluation of product and service experience to provide better value to users. He has played a vital role in the establishment of Asia’s first National Institute of Ergonomics and is the founder of ACED (Asian ..
Professor Sei Kwang Hahn and co-workers in the Department of Materials Science and Engineering at POSTECH, and Professor Allan S. Hoffman at the University of Washington, have investigated various kinds of hydrogels developed for stem cell therapy as a regenerative medicine. Their work is published in the latest edition of Progress in Polymer Science (IF = 26.854), an international peer-reviewed scientific journal in the field of polymer science and engineering. The paper entitled “In situ-forming injectable hydrogels for regenerative medicine” describes advanced polymeric hydrogel..
Using POSTECH Professor Chulhong Kim’s custom-built high-resolution photoacoustic imager, researchers were able to examine the combination of nanonaps and photoacoustic tomography illuminated inside the intestine of a mouse. (Credit: Chulhong Kim) Millions of people worldwide who suffer from digestive diseases may soon have a safer alternative to traditional radiological techniques when visiting the hospital for imaging of the gastrointestinal tract. Researchers from the Pohang University of Science and Technology (POSTECH), the University at Buffalo, and University of Wisconsin&ndas..
Noise plays a key role in important biological processes, such as bacterial antibiotics resistance, cancer development, and stem cell differentiation. Physics can explain much of this biological phenomenon. Professor Nam Ki Lee of the Department of Physics and the School of Interdisciplinary Bioscience and Bioengineering with Department of Physics graduate students Sora Yang, Seunghyeon Kim, Cheolhee Kim, Hyeong Jeon An and Professor Jaeyoung Sung of Chung-Ang University studied how cells propagate noise using RNA polymerase. Their research was published in this month’s Nature Communica..
Professor Yoon-Seok Chang (School of Environmental Science and Engineering), a worldwide authority on dioxin, has been selected as a first prize winner of the academic research award by the Korean Society of Environmental Engineers. An awards ceremony was held at the Kimdaejung Convention Center on August 21st. Over the past 30 years, Professor Chang has published nearly 200 SCI papers and studies which include analyses of toxic substances such as dioxins and other endocrine on human health. His study of the environmental risks of bio-nanomaterials has recently received academic attention.
Despite having numerous advantages, clinical applications of 3D printed scaffolds for tissue regeneration are extremely rare. A team consisting of POSTECH Professor of Mechanical Engineering Dong-Woo Cho, Professor Jong Won Rhie of the Department of Plastic Surgery College of Medicine at the Catholic University of Korea, and Won-Soo Yun of T&R Biofab Co., have applied 3D printing technology for correcting an asymmetric face caused by the removal of a tumor in a patient about a decade ago.The patient had trauma in the right malar region and because of this his eyes were misaligned. In this ..
The fundamental concepts of physics are crucial to understanding the correlation of the structure and strength of materials. Some materials, like a steel coil spring or rubber, are elastic. Grasping a rubber ball deforms the shape momentarily before it returns to its original state. Other materials when manipulated with, such as clay, will retain its newly deformed shape. This phenomenon, called plasticity, has been studied by scientists in designing high strength steels and alloys. The demand for high-technology metallic materials continues to depend on further research and understanding of ..
POSTECH Department of Chemical Engineering Professor Hyung Joon Cha and his team’s research on bone graft material binder technology was published in the Journal of Materials Chemistry B.Mussels stick to rocks because its protein has strong adhesive properties. This protein has been used as a binder for bodily wounds and surgery. An engineered mussel glue protein,a promising functional binder for the acceleration of bone substitute-assisted bone regeneration,has been developed by the joint research team of POSTECH and Korea University Anam Hospital, which can be used in teeth implants. ..