교원프로필

황철상 사진
교원에 대한 정보를 나타내는 표입니다.
성명 황철상
소속 생명과학과
전화번호 279-2352
E-mail cshwang@postech.ac.kr
Homepage https://cshwanglab.wixsite.com/homepage

학력

  • 1996.03 ~ 2000.08 서울대학교 (박사-)
  • 1994.03 ~ 1996.02 서울대학교 (석사-)
  • 1990.03 ~ 1994.02 서울대학교 (학사-)

주요경력

  • 2009.03 ~ 2011.02 : CALTECH DIVISION OF BIOLOGY
  • 2003.03 ~ 2009.02 : CALTECH DIVISION OF BIOLOGY
  • 2000.09 ~ 2003.02 : 서울대학교 생명과학부

전문분야

학술지

국제전문학술지

  • Cross-Species Functional Conservation and Possible Origin of the N-Terminal Specificity Domain of Mitochondrial Presequences, FRONTIERS IN PLANT SCIENCE, , 11, - (2020)
  • N-terminal acetylation and the N-end rule pathway control degradation of the lipid droplet protein PLIN2, JOURNAL OF BIOLOGICAL CHEMISTRY, , 294, 379-388 (2019)
  • N-terminal methionine excision of proteins creates tertiary destabilizing N-degrons of the Arg/N-end rule pathway, Journal of Biological Chemistry, , 294, 4464-4476 (2019)
  • Control of protein degradation by N-terminal acetylation and the N-end rule pathway, Experimental and Molecular Medicine, , 50, 91-8 (2018)
  • Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway, SCIENCE, , 362, 1019-+ (2018)
  • N-Terminal Acetylation-Targeted N-End Rule Proteolytic System: The Ac/N-End Rule Pathway, Molecules and Cells, , 39, 169-178 (2016)
  • SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins, MOLECULAR CELL, , 62, 7-20 (2016)
  • Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway, JOURNAL OF BIOLOGICAL CHEMISTRY, , 291, 17178-17196 (2016)
  • Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway, SCIENCE, , 347, 1249-1252 (2015)
  • Formyl-methionine as a degradation signal at the N-termini of bacterial proteins, Microbial Cell, , 2, 376-393 (2015)
  • Crystal Structure of the Rad3/XPD regulatory domain of Ssl1/p44, JOURNAL OF BIOLOGICAL CHEMISTRY, , 290, 8321-8330 (2015)
  • Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome, PLOS ONE, , 10, - (2015)
  • The N-terminal methionine of cellular proteins as a degradation signal, Cell, , 156, 158-169 (2014)
  • Synthetic lethal screen of NAA20, a catalytic subunit gene of NatB N-terminal acetylase in Saccharomyces cerevisiae, The Journal of Microbiology, , 52, 842-848 (2014)
  • Crosstalk between the Arg/N-end and Ac/N-end rule, CELL CYCLE, , 13, 1366-1367 (2014)
  • Synthetic Lethal Screen of NAA20, a Catalytic Subunit Gene of NatB N-Terminal Acetylase in Saccharomyces cerevisiae, JOURNAL OF MICROBIOLOGY, , 52, 842-848 (2014)
  • Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway, Molecular Cell, , 50, 540-551 (2013)
  • Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome, PLOS ONE, , 6, E24925- (2011)
  • N-terminal acetylation of cellular proteins creates specific degradation signals, SCIENCE, , 327, 973-977 (2010)
  • The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases, NATURE CELL BIOLOGY, , 12, 1177-1185 (2010)
  • Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 106, 2141-2147 (2009)
  • Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 105, 19188-19193 (2008)
  • Amino acids induce peptide uptake via accelerated degradation of CUP9, a transcriptional repressor of the PTR2 peptide transporter, JOURNAL OF BIOLOGICAL CHEMISTRY, , 283, 28958-28968 (2008)

국내전문학술지

일반학술지

학술회의논문

학회발표

  • Synthesis and degradation of proteins via formyl-methionine in eukaryotes, 2019 Cell Logistics Research Center Group2 Workshop Cellular & Molecular Logistics, 0, 0, - (2019)
  • N-terminal methionine excision of proteins creates tertiary destabilizing N-degron of the Arg/N-end rule pathway, N-terminal methionine excision of proteins creates tertiary destabilizing N-degron of the Arg/N-end rule pathway, 0, 0, - (2019)
  • The Beginning for the End of Proteins, The Beginning for the End of Proteins, 0, 0, - (2019)
  • N-Terminal Acetylation and the N-Degron Pathway, N-Terminal Acetylation and the N-Degron Pathway, 0, 0, - (2019)
  • Control of protein degradation by N-terminal acetylation and the N-end rule pathway, Control of protein degradation by N-terminal acetylation and the N-end rule pathway, 0, 0, - (2019)
  • The beginning for the End of Proteins: Discovery of New Protein Degradation Signals, The beginning for the End of Proteins: Discovery of New Protein Degradation Signals, 0, 0, - (2018)
  • Formyl-methionine-targeting proteolytic system: the fMet/N-end rule pathway, Formyl-methionine-targeting proteolytic system: the fMet/N-end rule pathway, 0, 0, - (2018)
  • Formyl-Methionine-Targeting Proteolytic System: the fMet/N-End Rule Pathway in the Yeast Saccharomyces cerevisiae, Formyl-Methionine-Targeting Proteolytic System: the fMet/N-End Rule Pathway in the Yeast Saccharomyces cerevisiae, 0, 0, - (2018)
  • Formyl-methionine acts as a specific protein degradation signal in the yeast Saccharomyces cerevisiae, Formyl-methionine acts as a specific protein degradation signal in the yeast Saccharomyces cerevisiae, 0, 0, - (2018)
  • Screening N-terminally formylated cytosolic proteins in Saccharomyces cerevisiae for investigating the novel degradation signal, Formy/N-degron, 분자세포생물학회 제29회 동계학술대회, 0, 0, - (2018)
  • Screening N-terminally formylated cytosolic proteins in Saccharomyces cerevisiae for investigating the novel degradation signal, Formy/N-degron, Screening N-terminally formylated cytosolic proteins in Saccharomyces cerevisiae for investigating the novel degradation signal, Formy/N-degron, 0, 0, - (2018)
  • Control of G-protein signaling by N-terminal acetylation and the N-end rule pathway, ., 0, 0, - (2017)
  • Proteolytic signals in yeast, Proteolytic signals in yeast, 0, 0, - (2017)
  • Control Protein Degradation by N-terminal Acetylation and the N-end Rule Pathway, N-term 2017: Proteostasis via the N-terminus, 0, 0, - (2017)
  • Control of G-protein signaling by N-terminal acetylation and the N-end rule pathway, 2017 Fall International Convention of The Pharmaceutical Society of Korea, 0, 0, - (2017)
  • N-terminal Acetylation-Dependent Autodegradation of an Ac/N-Recognin, TEB4 E3 Ubiquintin ligese, 2017 International Protein Metabolism&Diseases Conference, 0, 0, - (2017)
  • N-Terminal acetylation and N-terminal formylation of eukaryotic proteins act as specific degradation signals, KSBMB International Conference 2017, 0, 0, - (2017)
  • Nt-ACETYLATION DEPENDENT AUTODEGRADATION OF TEB4 E3 UBIQUITIN LIGASE PROVIDIES THE NEW INSIGT ABOUT THE FUNCTION OF Nt-ACETYLATION IN CHOLESTEROL HOMEOSTASIS, THE UBIQUINTIN FAMILY 2017, 0, 0, - (2017)
  • Novel Insights into Protein Turnover of Pro-opimelanocortin(POMC) and its Regulation by TEB4, RING Finger E3 Ubiquintin Lagase, ., 0, 0, - (2017)
  • N-terminal Formylation cretes specific degradation signals, ., 0, 0, - (2016)
  • Control of G-protein signaling by the N-terminal Acetylation and the N-end Rule proteolytic system, ., 0, 0, - (2016)
  • The beginning mark the End: The N-End rule proteolytic pathway, ., 0, 0, - (2016)
  • The beginning determines the End: The N-End rule proteolytic system, ., 0, 0, - (2016)
  • N-Terminal acetylation and formylation trigger protein degradation, ., 0, 0, - (2016)
  • Protein biogenesis and degradation through N-terminal methionine formylation in eukaryotes, ., 0, 0, - (2016)
  • The Arg/N-end rule substrates for N-terminal deamidation created by methionine aminopeptidases, ., 0, 0, - (2016)
  • The novel Arg/N-degron spawned by N-termonal methionine cleavage, ., 0, 0, - (2016)
  • Novel funtions of N-terminal formylatiom in Eukaryote, ., 0, 0, - (2016)
  • Identification of pomc and snapin as new substrates of the E3 Ubiquintin ligase, Teb4, ., 0, 0, - (2016)
  • New funtions of N-Terminal Protein Formylation, ., 0, 0, - (2015)
  • New funtctions of N-terminal protein formylation, ., 0, 0, - (2015)
  • G Protein signaling by N-Terminal Acetylation and the N-End Rule Pathway, ., 0, 0, - (2015)
  • Control of Mammalian G Protein signaling by N-terminal Acetylation and the N-end Rule Pathway, ., 0, 0, - (2015)
  • Functions and Mechanism of N-Terminal Acetylation and the N-End Rule proteolytic system, ., 0, 0, - (2015)
  • N-Terminal Acetylation and the N-End Rule Pathway for the Control of Mammalian G-Protein signaling, ., 0, 0, - (2015)
  • Functions of N-terminal methionine formylation in mitochondrial fatty acid synthesis in Saccharomyces cerevisiae, ., 0, 0, - (2015)
  • Control of Rgs2 by mammalian Ac/N-end rule pathway, ., 0, 0, - (2015)
  • N-Terminal Acetylation and the N-End Rule Pathway for G-protein coupled receptor Signaling, ., 0, 0, - (2015)
  • N-Terminal Acetylation and the N-End Rule Pathway for the Control of Mammalian G-Protein signaling, ., 0, 0, - (2015)
  • Functions of N-terminal methionine formylation in mitochondrial fatty acid synthesis in Saccharomyces cerevisiae, ., 0, 0, - (2015)
  • Methionine aminopeptidases creates the Arg/N-end rule substrates for N-terminal deamidation, ., 0, 0, - (2015)
  • Regulatory Proteolysis by N-Terminal Acetylation and the N-End Rule Pathway, ., 0, 0, - (2014)
  • Protein N-Terminal Acetylation and a New Branch of the N-End Rule Pathway, ., 0, 0, - (2014)
  • Complementarity of the Arg/N-End Rule Pathway and Ac/N-End Rule Pathway, ., 0, 0, - (2014)
  • Genome-Wide Synthetic Lethal Screen of NatB N-Terminal Acetylase in Saccharomyces cerevisiae, ., 0, 0, - (2014)
  • Protein N-Terminal Acetylation and a New Branch of the N-End Rule Pathway, ., 0, 0, - (2014)
  • Functions of Protein N-terminal formylation, ., 0, 0, - (2014)
  • N-terminal acetylation and the N-End rule pathway control degradation of RGS2, ., 0, 0, - (2014)
  • complementarity of the Ac/N-end rule pathway and the Arg/N-end rule pathway, ., 0, 0, - (2014)
  • Genome wide synthetic lethal screen of NatB N-terminal Acetylase in saccharomyces cerevisiae, ., 0, 0, - (2014)
  • Complementary Specificities of the Arg/N-End Rule Pathway and the Ac/N-End Rule Pathway, ., 0, 0, - (2014)
  • Trk-fuged Gene(TFG) and Histidine Triadnucleotide Binding Protein 2 (Hint2) as Putative Johanson-Blizzard Syndrome (JBS)-relevant Substrates of Human UBR1, ., 0, 0, - (2014)
  • Complementary Specificities of the Arg/N-End Rule Pathway and the Ac/N-End Rule Pathway, ., 0, 0, - (2014)
  • Trk-fuged Gene(TFG) and Histidine Triadnucleotide Binding Protein 2 (Hint2) as Putative Johanson-Blizzard Syndrome (JBS)-relevant Substrates of Human UBR1, ., 0, 0, - (2014)
  • The N-Terminal Methionine of Cellular Proteins as a Degradation Signal, ., 0, 0, - (2013)
  • The N-Terminal Methionine of Cellular Proteins as a Degradation Signal, ., 0, 0, - (2013)
  • The Acetylation/N-End Rule and Arginine/N-End Rule Pathway, ., 0, 0, - (2013)
  • The Acetylation/N-End Rule and Arginine/N-End Rule Pathway, ., 0, 0, - (2013)
  • N-terminal acetylation and the N-end rule pathway control degradation of RGS2, ., 0, 0, - (2013)
  • Acetylated and Unacetylated N-Termini of Cellular Proteins as N-Degrons of the N-End Rule Pathway, ., 0, 0, - (2013)
  • Acetylated and Unacetylated N-Termini of Cellular Proteins as N-Degrons of the N-End Rule Pathway, ., 0, 0, - (2013)
  • Functions of N-Terminal Acetylation for Protein Stability, ., 0, 0, - (2012)
  • Functions of N-Terminal Acetylation for Protein Stability, ., 0, 0, - (2012)
  • Cytoplasmic Protein Quality Control by the Two N-End Rule Pathways, ., 0, 0, - (2012)
  • The Arg/N-end rule pathway targets N-terminally unacetyalted proteins, ., 0, 0, - (2012)
  • N-terminal acetylation-mediated protein degradation pathway, ., 0, 0, - (2011)
  • N-Terminal Acetylation-Mediated Protein Degradation Pathway, ., 0, 0, - (2011)
  • The N-end rule pathway of the ubiquitin-mediated proteolysis, ., 0, 0, - (2011)

단행본

연구실적

  • N-말단 아미노산 아세틸레이션의한 단백질 분해 경로 연구, 포항공대산학협력단 (2011-2012)
  • 신규부임교수 기자재구입비(생명), 포항공과대학교 (2011-2012)
  • N-말단 아미노산과 유비퀴틴에 의한 단백질 분해, 포항공과대학교 (2011-2012)
  • 휴먼질환과 관련된 N-말단 아세틸레이션 단백질 분해 연구, 재단법인한국연구재단 (2011-2012)
  • 조한슨-블리자드 증후군 발병 기전을 통한 췌장질환 연구, 한국보건산업진흥원 (2011-2012)
  • O6-알킬구아닌 DNA 알킬랜스퍼라제 분해연구, 포항공과대학교 (2012-2013)
  • 학부생연구프로그램-김헌기(생명)-효모에서 단백질 N-말단 포밀레이션 기능연구, 포항공과대학교 (2012-2012)
  • (학생)인건비풀링과제, 포항공대산학협력단 (2012-2020)
  • 휴먼질환과 관련된 N-말단 아세틸레이션 단백질 분해 연구, 재단법인한국연구재단 (2012-2013)
  • 조한슨-블리자드 증후군 발병 기전을 통한 췌장질환 연구, 한국보건산업진흥원 (2012-2013)
  • 2013 미토콘드리아 컨퍼런스, 포항공과대학교 (2013-2014)
  • 단백질 메틸시스테인 디메틸라제 탐색과 생리적 기능 연구, 재단법인한국연구재단 (2013-2014)
  • 휴먼질환과 관련된 N-말단 아세틸레이션 단백질 분해 연구, 재단법인한국연구재단 (2013-2014)
  • 조한슨-블리자드 증후군 발병 기전을 통한 췌장질환 연, 한국보건산업진흥원 (2013-2014)
  • N-말단 포밀레이션 단백질 분해 경로 연구, 재단법인 삼성미래기술육성재단 (2014-2015)
  • 단백질 메틸시스테인 디메틸라제 탐색과 생리적 기능 연구, 재단법인한국연구재단 (2014-2015)
  • 단백질 메틸시스테인 디메틸라제 탐색과 생리적 기능 연구, 재단법인한국연구재단 (2015-2016)
  • 이월과제_4.11034, 재단법인 삼성미래기술육성재단 (2015-2015)
  • N-말단 포밀레이션 단백질 분해 경로 연구, 재단법인 삼성미래기술육성재단 (2014-2017)
  • [학부생연구프로그램]식욕 조절 단백질, Α-MSH의 체내 조절 기작 연구, 포항공과대학교 (2016-2016)
  • N-말단 포밀레이션 단백질 분해 경로 연구, 재단법인 삼성미래기술육성재단 (2016-2019)
  • [GS4차]악성종양 치료를 위한 시스테인 탈메틸화 효소 연구, (주)포스코 (2017-2018)
  • 진핵생물 포밀메티오닌 단백질 합성과 분해 연구, 재단법인 삼성미래기술육성재단 (2019-2020)
  • N-말단 암호 인식 단백질 분해신호 경로 연구, 재단법인한국연구재단 (2020-2021)
  • 단백질향상성연구소(리더)_부서운영비, 포항공대산학협력단 (2020-2021)

IP

  • 황철상,김다솜,.Nguyen The Kha, 고순도 유비퀴틴의 정제방법, 한국, 10-2019-0179913 (2019)
  • 황철상,석옥희,김정목, N-말단 포밀화 유도를 통한 진핵세포 단백질의 분해 조절방법, 한국, 10-2019-0066978 (2019)
  • 황철상,문상현,이창석,.Nguyen The Kha, N-말단 아세틸화에 의한 페릴리핀2 단백질의 분해 조절 및 이를 이용한 지방 방울 조절방법, 한국, 10-2019-0057538 (2019)
  • 황철상,김정목, N-말단 메티오닌에 의한 단백질 분해 조절, 한국, 10-2014-0137805 (2014)
  • 황철상,김정목, N-말단 메티오닌에 의한 단백질 분해 조절, 한국, 10-2014-0137805 (2014)