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POSTECH

Education

  • 2003.03 ~ 2006.02 서울대학교 (박사-)
  • 2001.03 ~ 2003.02 서울대학교 (석사-)
  • 1994.03 ~ 2001.02 서울대학교 (학사-)

Career

  • 2007.01 ~ 2011.07 HOWARD HUGHES MEDICAL INSTITUTE
  • 2006.03 ~ 2006.12 서울대학교

Journal Papers

International
  • ETV5 promotes lupus pathogenesis and follicular helper T cell differentiation by inducing osteopontin expression, Proceedings of the National Academy of Sciences of the United States of America, , 121, - (2024 )
  • Cytosolic Nterminal formylmethionine deformylation derives cancer stem cell features and tumor progression, Scientific Reports, , 14, - (2024 )
  • The capicuaataxin1like complex regulates Notchdriven marginal zone B cell development and sepsis progression, Nature Communications, , 15, - (2024 )
  • The transcription factor Mef2d regulates BT synapse–dependent GCTFH differentiation and IL21–mediated humoral immunity, Science immunology, , 8, - (2023 )
  • The ubiquitin–proteasome system links NADPH metabolism to ferroptosis, Trends in Cell Biology, , 33, 1088-1103 (2023 )
  • Postnatal regulation of B1a cell development and survival by the CICPER2BHLHE41 axis, Cell Reports, , 38, - (2022 )
  • Generation of hematopoietic lineage cellspecific chimeric mice using retrovirustransduced fetal liver cells, STAR Protocols, , 3, - (2022 )
  • The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis, Nature Cell Biology, , 24, 1239-+ (2022 )
  • ERK phosphorylation disrupts the intramolecular interaction of capicua to promote cytoplasmic translocation of capicua and tumor growth, Frontiers in Molecular Biosciences, , 9, - (2022 )
  • Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua, ELIFE, , 10, - (2021 )
  • Capicua restricts cancer stem celllike properties in breast cancer cells, Oncogene, , , - (2020 )
  • Capicua suppresses colorectal cancer progression via repression of ETV4 expression, Cancer Cell International, , 20, - (2020 )
  • Regulation and function of capicua in mammals, EXPERIMENTAL AND MOLECULAR MEDICINE, , 52, 531-537 (2020 )
  • Deletion Timing of Cic Alleles during Hematopoiesis Determines the Degree of Peripheral CD4 T Cell Activation and Proliferation, IMMUNE NETWORK, , 20, - (2020 )
  • Haploinsufficiency of Cyfip2 Causes LithiumResponsive Prefrontal Dysfunction, Annals of neurology, , 88, 526-543 (2020 )
  • The CapicuaETS Translocation Variant 5 Axis Regulates LiverResident Memory CD8 TCell Development and the Pathogenesis of Liver Injury, HEPATOLOGY, , 70, 358-371 (2019 )
  • Costeffective production of tagless recombinant protein in Nicotiana benthamiana, PLANT BIOTECHNOLOGY JOURNAL, , 17, 1094-1105 (2019 )
  • Capicua suppresses hepatocellular carcinoma progression by controlling ETV4MMP1 axis, HEPATOLOGY, , 67, 2287-2301 (2018 )
  • Translational control of phloem development by RNA GquadruplexJULGI determines plant sink strength, NATURE PLANTS, , 4, 376-+ (2018 )
  • Genomewide CRISPRCas9 Screen Identifies Host Factors Essential for Influenza Virus Replication, Cell Reports, , 23, 596-607 (2018 )
  • Disruption of the ATXN1CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans, Nature Genetics, , 49, 527-536 (2017 )
  • Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5., Nature Communications, , 8, 16037- (2017 )
  • Hypoxia-inducible factor-1α regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice, Oncotarget, , 8, 111508-111521 (2017 )
  • Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5, Nature Communications, , 8, 10637- (2017 )
  • Hypoxiainducible factor1 alpha regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice, Oncotarget, , 8, 111508-111521 (2017 )
  • Replenishment of microRNA1885p restores the synaptic and cognitive deficits in 5XFAD Mouse Model of Alzheimer’s Disease, Scientific Reports, , 6, - (2016 )
  • Deficiency of Capicua disrupts bile acid homeostasis, Scientific Reports, , 5, - (2015 )
  • miR93miR106bmiR375CICCRABP1 a novel regulatory axis in prostate cancer progression, ONCOTARGET, , 6, 23533-23547 (2015 )
  • Capicua as a negative regulator of the pathogenesis of hepatocellular carcinoma, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, , 36, S95-S95 (2015 )
  • RNA helicase HEL1 promotes longevity by specifically activating DAF16FOXO transcription factor signaling in Caenorhabditis elegans, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 112, E4246-E4255 (2015 )
  • Humanspecific regulation of MeCP2 levels in fetal brains by microRNA miR4835p, GENES DEVELOPMENT, , 27, 485-490 (2013 )
  • Ataxin1L is a regulator of HSC function highlighting the utility of crosstissue comparisons for gene discovery, PLOS GENETICS, , 9, - (2013 )
  • RAS–MAPK–MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1, Nature, , 498, 325- (2013 )
  • ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization, DEVELOPMENTAL CELL, , 21, 746-757 (2011 )
  • miR19 miR101 and miR130 coregulate ATXN1 levels to potentially modulate SCA1 pathogenesis, Nature Neuroscience, , 11, 1137-1139 (2008 )

IP

  • 황철상,이종은,.Nguyen The Kha,김다솜,이윤태, MARCH6 저해제를 포함하는, 항암용 조성물, -, PCT/KR2022/0195 (2022)
  • 황철상,김다솜,이종은,이윤태,.Nguyen The Kha, MARCH6 저해제를 포함하는, 항암용 조성물, 한국, 10-2022-0006597 (2021)
  • 황철상,김다솜,이종은,이윤태,.Nguyen The Kha, MARCH6 저해제를 포함하는, 항암용 조성물, 한국, 10-2022-0006597 (2021)
  • 황인환,이윤태,Islam Md Reyazul,이전수,곽주원,이용직, 식물에서 단백질의 분리정제를 위한 재조합 벡터, 한국, 10-2017-0117174 (2017)

Invited Talk or Presentations

  • Role of CICATXN1ATXN1L complex in innatelike B cell development , , 0, 0, - (2022)
  • ETV5 promotes Tfh cell differentiation and the pathogenesis of systemic lupus erythematosus, , 0, 0, - (2022)
  • Transcriptional Regulation of B1 and B2 Cell Fates by Capicua, E4 B Cells Mechanisms in Immunity and Autoimmunity, 0, 0, - (2018)

Research Activities

  • ROLE OF CIC TRANSCRIPTION REPRESSOR IN CARCER PROGRESSION, 포항공과대학교 (2011-2012)
  • , 포항공과대학교 (2011-2012)
  • , 포항공과대학교 (2012-2013)
  • , 포항공과대학교 (2012-2013)
  • ROLE OF CIC-ATXN1/ATXN1L TRANSCRIPTIONAL REPRESSOR COMPLEXES IN BREAST CANCER DEVELOPMENT AND METASTASIS, 재단법인한국연구재단 (2012-2013)
  • , 포항공과대학교 (2012-2012)
  • , 포항공과대학교 (2013-2015)
  • (학생)인건비풀링과제, 포항공대산학협력단 (2013-2020)
  • ROLE OF CIC-ATXN1/ATXN1L TRANSCRIPTIONAL REPRESSOR COMPLEXES IN BREAST CANCER DEVELOPMENT AND METASTASIS, 재단법인한국연구재단 (2013-2014)
  • , 포항공과대학교 (2014-2015)
  • Role of CIC-ATXN1/ATXN1L transcriptional repressor complexes in breast cancer development and metastasis, 재단법인한국연구재단 (2014-2015)
  • Role of CIC-ATXN1/ATXN1L transcriptional repressor complexes in breast cancer development and metastasis, 재단법인한국연구재단 (2014-2015)
  • ROLE OF CIC-ATXN1/ATXN1L TRANSCRIPTIONAL REPRESSOR COMPLEXES IN BREAST CANCER DEVELOPMENT AND METASTASIS, 재단법인한국연구재단 (2014-2015)
  • , (재)포항테크노파크 (2014-2014)
  • 동남권 R&D기관 우수기술 발굴지원사업, (재)포항테크노파크 (2014-2014)
  • , 포항공과대학교 (2015-2016)
  • ELUCIDATION OF MOLECULAR MECHANISM UNDERLYING CRABP1-MEDIATED PROMOTION OF PROSTATE CANCER PROGRESSION, 재단법인한국연구재단 (2015-2016)
  • , 포스코홀딩스(주) (2015-2016)
  • , 포항공대산학협력단 (2015-2040)
  • 축산분뇨 재활용을 통한 자원화사업, (재)포항테크노파크 (2015-2016)
  • IDENTIFICATION AND FUNCTIONAL STUDY OF NOVEL KEY FACTORS THAT REGULATE T CELL ACTIVATION AND PATHOGENESIS OF AUTOIMMUNE DISEASES, 재단법인 삼성미래기술육성재단 (2015-2018)
  • ELUCIDATION OF MOLECULAR MECHANISM UNDERLYING CRABP1-MEDIATED PROMOTION OF PROSTATE CANCER PROGRESSION, 재단법인한국연구재단 (2016-2017)
  • , 재단법인한국연구재단 (2017-2018)
  • , 재단법인한국연구재단 (2017-2018)
  • , 재단법인 삼성미래기술육성재단 (2017-2020)
  • ROLE OF CAPICUA IN THE DEVELOPMENT OF CASTRATION-RESISTANT PROSTATE CANCER, 재단법인한국연구재단 (2018-2019)
  • , 재단법인한국연구재단 (2019-2020)
  • , 재단법인한국연구재단 (2020-2021)
  • IDENTIFICATION OF NOVEL LINKS BETWEEN CIRRHOSIS AND HEPATOCELLULAR CARCINOMA THROUGH MECHANISMS OF MICROSPHERULE PROTEIN 1, 재단법인한국연구재단 (2020-2021)
  • NOVEL GENES THAT REGULATE NEURONAL CELL DEATH, 재단법인한국연구재단 (2020-2021)
  • TRANSCRIPTIONAL REGULATION OF THE DEVELOPMENT AND FUNCTIONS OF INNATE-LIKE B CELL SUBSETS BY CIC-ATXN1L COMPLEX, 재단법인한국연구재단 (2021-2022)
  • ROLES OF COMMENSAL PAPILLOMAVIRUSES IN MAINTAINING SKIN HOMEOSTASIS, 재단법인한국연구재단 (2021-2022)
  • , 재단법인한국연구재단 (2022-2023)
  • , 재단법인한국연구재단 (2022-2023)
  • THERAPEUTIC APPROACHES TO NEUROENDOCRINE PROSTATE CANCER THROUGH DEVELOPING ETV5 INHIBITORS, 과학기술정보통신부 (2022-2022)
  • , 과학기술정보통신부 (2023-2023)
  • , 재단법인한국연구재단 (2023-2024)
  • , 재단법인한국연구재단 (2023-2024)
  • , 포항공과대학교 (2024-2024)
  • , 포항공과대학교 (2024-2025)
  • REGULATION OF DENDRITIC CELL DEVELOPMENT AND FUNCTION BYTHE TRANSCRIPTIONAL REPRESSOR CAPICUA, 재단법인한국연구재단 (2024-2025)

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