Research

International

• Synthesis and Structural Characterization of Macrocyclic αABpeptoids and Their DNAEncoded Library, Organic Letters, , 26, 1100-1104 (2024 )
• Aptamer and NDegron Ensemble AptaGron as a Target Protein Degradation Strategy, ACS chemical biology, , 19, 2462-2468 (2024 )
• Evaluation of the cell permeability of bicyclic peptoids and bicyclic peptidepeptoid hybrids, Bioorganic Chemistry, , 127, - (2022 )
• Cationic amphipathic small molecules based on a triazinepiperazinetriazine scaffold as a new class of antimicrobial agents, European Journal of Medicinal Chemistry, , 243, - (2022 )
• Synthesis of a DNAEncoded Library of Pyrrolo23dpyrimidines, Bulletin of the Korean Chemical Society, , 42, 691-698 (2021 )
• Hydrophobic TaggingMediated Degradation of Transcription Coactivator SRC1, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, , 22, - (2021 )
• Onebeadonecompound screening approach to the identification of cyclic peptoid inhibitors of cyclophilin D as neuroprotective agents from mitochondrial dysfunction, CHEMICAL COMMUNICATIONS, , 57, 2388-2391 (2021 )
• Design and synthesis of a DNAencoded combinatorial library of bicyclic peptoids, BIOORGANIC amp MEDICINAL CHEMISTRY, , 48, - (2021 )
• Cellpenetrating amphipathic cyclic peptoids as molecular transporters for cargo delivery, Chemical Communications, , 57, 6800-6803 (2021 )
• Targeted Degradation of Transcription Coactivator SRC1 through the NDegron Pathway, ANGEWANDTE CHEMIEINTERNATIONAL EDITION, , 59, 17548-17555 (2020 )
• SolidPhase Synthesis and Circular Dichroism Study of ABpeptoids, MOLECULES, , 24, - (2019 )
• A solidphase method for synthesis of dimeric and trimeric ligands Identification of potent bivalent ligands of 1433 sigma, BIOORGANIC CHEMISTRY, , 91, - (2019 )
• Oligomers of alphaABpeptoidbeta3peptide hybrid, BIOPOLYMERS, , 110, - (2019 )
• DNAEncoded Combinatorial Library of Macrocyclic Peptoids, BIOCONJUGATE CHEMISTRY, , 30, 2931-2938 (2019 )
• Bridged alphahelix mimetic small molecules, CHEMICAL COMMUNICATIONS, , 55, 13311-13314 (2019 )
• Comparison of Cell Permeability of Cyclic Peptoids and Linear Peptoids, ACS COMBINATORIAL SCIENCE, , 20, 237-242 (2018 )
• Submonomer Strategy toward Divergent SolidPhase Synthesis of alphaABpeptoids, ORGANIC LETTERS, , 20, 2526-2529 (2018 )
• Colorectal Cancer Diagnosis Using EnzymeSensitive Ratiometric Fluorescence Dye and Antibody–Quantum Dot Conjugates for Multiplexed Detection, ADVANCED FUNCTIONAL MATERIALS, , 28, 1703450- (2018 )
• A Forkhead Box ProteinC2 Inhibitor Targeting EpithelialMesenchymal Transition and Cancer Metastasis, ChemBioChem, , 19, 1359-1364 (2018 )
• Design developments and preliminary circular dichroism spectroscopic investigations of alphabetaABpeptoids A class of betapeptoids with backbone chirality, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, , 256, - (2018 )
• Comparison of the Cell Permeability of Linear and Cyclic Peptoids, Journal of Peptide Science, , 24, S119-S119 (2018 )
• Development of the Stapled Peptide Targeting the NCOA1STAT6 ProteinProtein Interaction, Journal of Peptide Science, , 24, S158-S158 (2018 )
• Evaluation of Cell Permeability of Bicyclic Peptoids, Journal of Peptide Science, , 24, S119-S119 (2018 )
• Triazinebridged cyclic peptoids as molecular transporters Applications in drug delivery, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, , 256, - (2018 )
• Intracellular and transdermal protein delivery mediated by noncovalent interactions with a synthetic guanidinerich molecular carrier, International Journal of Pharmaceutics, , 528, 646-654 (2017 )
• Targeted Inhibition of the NCOA1STAT6 ProteinProtein Interaction, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, , 139, 16056-16059 (2017 )
• Screening methods for identifying pharmacological chaperones, Molecular BioSystems, , 13, 638-647 (2017 )
• A chemical inhibitor of the Skp2p300 interaction that promotes p53mediated apoptosis, ANGEWANDTE CHEMIEINTERNATIONAL EDITION, , 55, 602-606 (2016 )
• Converting OneFace αHelix Mimetics into Amphiphilic αHelix Mimetics as Potent Inhibitors of ProteinProtein Interactions, ACS Combinatorial Science, , 18, 36-42 (2016 )
• Oligomers of NSubstituted β2Homoalanines Peptoids with Backbone Chirality, Organic Letters, , 18, 3878-3681 (2016 )
• Skp2 Inhibitors Novel Anticancer Strategies, Current Medicinal Chemistry, , 23, 2363-2379 (2016 )
• Chemical inhibitor of the Skp2p300 interaction that promotes p53mediated apoptosis, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, , 251, - (2016 )
• Synthesis and screening of smallmolecule alphahelix mimetic libraries targeting proteinprotein interactions, CURRENT OPINION IN CHEMICAL BIOLOGY, , 24, 38-47 (2015 )
• Design SolidPhase Synthesis and Evaluation of a PhenylPiperazineTriazine Scaffold as alphaHelix Mimetics, ACS COMBINATORIAL SCIENCE, , 16, 695-701 (2014 )
• Facile Method To Sequence Cyclic PeptidesPeptoids via OnePot RingOpeningCleavage Reaction, ORGANIC LETTERS, , 16, 5710-5713 (2014 )
• Potential pharmacological chaperones targeting cancerassociated MCL1 and Parkinson diseaseassociated alphasynuclein, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 111, 11007-11012 (2014 )
• Solidphase synthesis of tetrasubstituted pyrrolo23dpyrimidines, ORGANIC BIOMOLECULAR CHEMISTRY, , 10, 4229-4235 (2012 )
• Design and Facile SolidPhase Synthesis of Conformationally Constrained Bicyclic Peptoids, ORGANIC LETTERS, , 13, 5012-5015 (2011 )
• Novel PyrrolopyrimidineBased alphaHelix Mimetics CellPermeable Inhibitors of ProteinProtein Interactions, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, , 133, 676-679 (2011 )
• A simple strategy for the construction of combinatorial cyclic peptoid libraries, CHEMICAL COMMUNICATIONS, , 46, 8615-8617 (2010 )
• Potent and selective photoinactivation of proteins with peptoidruthenium conjugates, NATURE CHEMICAL BIOLOGY, , 6, 258-260 (2010 )
• Nonproteolytic Regulation of p53mediated Transcription through Destabilization of the ActivatorPromoter Complex by the Proteasomal ATPases, JOURNAL OF BIOLOGICAL CHEMISTRY, , 284, 34522-34530 (2009 )
• Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle, CHEMICAL COMMUNICATIONS, , , 1064-1066 (2008 )
• Periodatetriggered crosslinking reveals Sug2Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, , 129, 12936- (2007 )
• Identification of a peptoid inhibitor of the proteasome 19S regulatory particle, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, , 129, 7750- (2007 )
• Design and synthesis of a cellpermeable synthetic transcription factor mimic, JOURNAL OF COMBINATORIAL CHEMISTRY, , 9, 592-600 (2007 )
• A cellpermeable synthetic transcription factor mimic, ANGEWANDTE CHEMIEINTERNATIONAL EDITION, , 46, 2865-2868 (2007 )

Invited Talk or Presentations

• Design Synthesis and Circular Dichrosism Studies of a New Class of Heterogeneous Foldamers β3PeptideαABpeptoid Hybrid Oligomers , , 0, 0, - (2018)
• Targeted Protein Degradation Using NEnd Rule Pathway , , 0, 0, - (2018)
• Identification of potential mETV5 modulator via a DNAencoded Cyclic PeptidePeptoid Hybrid Library , , 0, 0, - (2018)
• Development of the Inhibitor Targeting NCOA1STAT6 Interaction Based on the StructureActivity Relationship SAR study , , 0, 0, - (2018)
• Identification of Cyclic Peptoid Inhibitors of Skp2 Using a Vast DNAEncoded OneBead OneCompound Library , , 0, 0, - (2018)
• Comparison of Cell Permeability of Bicyclic Peptoids and Linear Peptoids , , 0, 0, - (2018)
• Synthesis of a Vast DNAEncoded Cyclic Peptoid Library to Identification of Skp2 Inhibitors , , 0, 0, - (2018)
• Conformational Study of Cyclic αABpeptoids , , 0, 0, - (2018)
• Development of Novel Proteolysis Targeting Chimeras Using NEnd Rule Pathway , , 0, 0, - (2018)
• Evaluation of Cell Permeability of Bicyclic Peptoids , , 0, 0, - (2018)
• Comparison of the Cell Permeability of Linear and Cyclic Peptoids , , 0, 0, - (2018)
• Development of the Stapled Peptide Targeting the NCOA1STAT6 ProteinProtein Interaction , , 0, 0, - (2018)
• Triazinebridged cyclic peptoids as molecular transporters Applications in drug delivery , , 0, 0, - (2018)
• Targeted Inhibition of the NCOA1STAT6 ProteinProtein Interaction , , 0, 0, - (2018)
• Comparison of Cell Permeability between Linear Peptoids and Cyclic Peptoids , , 0, 0, - (2018)
• Triazinebridged cyclic peptoids as molecular transporters , , 0, 0, - (2017)
• Stapled αHelix Mimetic SmallMolecules Targeting Mcl1 , , 0, 0, - (2017)
• Design Synthesis and CD Spectroscopy Investigation of αAbpeptoidsβpeptides Hybrid Oligomers , , 0, 0, - (2017)
• Identification of Skp2 Inhibitors using a DNAEncoded Cyclic Peptoid Library , , 0, 0, - (2017)
• Oligomers of NSubstituted β2 and β3 Homoalanines A Novel Class of BetaPeptoids with Backbond Chirality , , 0, 0, - (2017)
• Synthesis and Circular Dichroism Studies of ABpeptoidsβpeptides Hybrid Oligomers , , 0, 0, - (2017)
• OnePot Synthesis of Novel Bivalent Phosphopeptide Targeting 1433σ , , 0, 0, - (2017)
• Identification of Peptidomimetic Inhibitors of Skp2 using a Vast OneBead OneCompound Library , , 0, 0, - (2017)
• Design Synthesis and Circular Dichroism Studies of Novel Hybrid Oligomers with Backbone Chirality , , 0, 0, - (2017)
• Development of Molecular Transporter Based on Cyclic Poly Peptoids , , 0, 0, - (2017)
• Synthesis and CD Spectroscopic Studies of a New Class of PeptoidBased Foldamers Nsubstituted β2 or β3Homoalanines , , 0, 0, - (2017)
• Identification of Peptidomimetic Inhibitors of Skp2 , , 0, 0, - (2017)
• Assessment of Cell Permeability of Cyclic Peptoids and Linear Peptoids , , 0, 0, - (2017)
• Development of a Stapled Peptide Inhibitor Targeting NCoA1STAT6 Interaction , , 0, 0, - (2017)
• Oligomers of NSubstituted β2Homoalanines as Antimicrobial Agents , , 0, 0, - (2017)
• Design triazine assisted potent bivalent phosphopeptide for targeting 1433σ , , 0, 0, - (2017)
• New class of hybrid oligomers with backbone chirality , , 0, 0, - (2017)
• Construction and highthroughput screen of an ultralarge bead library for rapid discovery of potent protein binding ligands , , 0, 0, - (2016)
• Construction of a Vast OneBead OneCompound Library of Cyclic Peptoids , , 0, 0, - (2016)
• Identification of a Chemical Inhibitor of the Skp2p300 Interaction , , 0, 0, - (2016)
• A Cyclic Peptoid Inhibitor of the Skp2p300 Interaction, , 0, 0, - (2016)
• Development of firstinclass NCoA1STAT6 inhibitor using stapled peptide , , 0, 0, - (2016)
• Design Synthesis and Cricular Dichroism Studies of Nsubstituted β2Homoalanines as a New Class of Peptoid Foldamers , , 0, 0, - (2016)
• Development of Amphiphilic Twoface αHelix Mimetics as Specific Modulators of ProteinProtein Interactions , , 0, 0, - (2016)
• Development of firstinclass NCoA1STAT6 inhibitor using stapled peptide , , 0, 0, - (2016)
• TwoFace Amphiphilic αHelix Mimetics as Potent Inhibitors of ProteinProtein Interactions , , 0, 0, - (2016)
• Identification of an Inhibitor of the Skp2p300 interaction that promotes p53mediated apoptosis , , 0, 0, - (2016)
• Converting OneFace aHelix Mimetics into Amphiphilic aHelix Mimetics as potent Inhibitors of ProteinProtein Interactions, , 0, 0, - (2016)
• Simple sequencing strategy for bicyclic peptoidspeptides via onepot ringopening and cleavage reaction , , 0, 0, - (2016)
• Stapled aHelix Mimetic SmallMolecules, , 0, 0, - (2016)
• A novel stabilization strategy of αhelix mimetic small molecules using hydrocarbon bridge, , 0, 0, - (2015)
• Cellular Uptake Evaluation of TriazineBridged Cyclic Peptoids, , 0, 0, - (2015)
• Design Synthesis and Antimicrobial Activities of a Facile Amphiphlic Peptidomimetics, , 0, 0, - (2015)
• SolidPhase Synthesis and Sequence Analysis of Small Molecule alphaHelix Mimetic Oligobenzamides, , 0, 0, - (2015)
• A OnePot RingOpening and Cleavage Strategy for Constructing a Combinatorial Library of Bicyclic Peptoids, , 0, 0, - (2015)
• Oligomers of NSubstituted β2Homoalanines New Peptoid Foldamers, , 0, 0, - (2015)
• A OnePot RingOpeningCleavage Reaction for Constructing Combinatorial Cyclic Peptoid Libraries, , 0, 0, - (2015)
• OnResin Protection for Efficient Sequence Determination of Cyclic Peptoids, , 0, 0, - (2015)
• A OnePot RingOpening and Cleavage Strategy for a Combinatorial Library of Bicyclic Peptoids, , 0, 0, - (2015)
• Synthetic Antimicrobial Peptidomimetics Using Facile Amphiphilic Helical Scaffold, , 0, 0, - (2015)
• A Facile Method for Sequence Determination of Cyclic PeptidesPeptoids via CNBrMediated OnePot RingOpeningCleavage Reaction, , 0, 0, - (2015)
• Design synthesis and evaluation of phenylpiperazinetriazinebased alhpahelix mimetics as protein capture reagents, , 0, 0, - (2015)
• Targeting ProteinProtein Interactions Using alphaHelix Mimetics with Easy Synthetic Manipulation, , 0, 0, - (2015)
• Onbead screening method for Rapid and Efficient Identification of αHelix Mimetics Targeting ProteinProtein Interactions, , 0, 0, - (2015)
• A Simple RingOpening Strategy for Cyclic Peptide and Cyclic Peptoid Libraries, , 0, 0, - (2015)
• StructureActivity Relationship Study of alphaHelix Mimetics Targeting ProteinProtein Interactions, , 0, 0, - (2015)
• A Simple Strategy for Sequence Determination of Cyclic PeptidesPeptoids via CNBrMediated OnePot RingOpeningCleavage Reaction, , 0, 0, - (2015)
• A Combinatorial Library Approach for Rapid and Efficient Identification of αHelix Mimetics Targeting ProteinProtein Interactions, , 0, 0, - (2015)