Research

국제전문학술지

• Tau condensation on DNA mediates microtubule attachment suggesting a mitotic role for centromerelocalized tau, Nature Communications, , 17, - (2026 )
• smDeepFLUOR singlemolecule deep learning fluorescence classification, Nature Communications, , 17, - (2026 )
• Singletrajectory Bayesian modeling reveals multistate diffusion of the MSH sliding clamp, npj Systems Biology and Applications, , 12, - (2026 )
• Attacking biological problems through singlemolecule approaches, BMB Reports, , 58, 1-1 (2025 )
• Cryogenic singlemolecule fluorescence imaging, BMB Reports, , 58, 2-7 (2025 )
• A novel ADPdirected chaperone function facilitates the ATPdriven motor activity of SARSCoV helicase, Nucleic Acids Research, , 53, - (2025 )
• DNA Hanger SurfaceMinimized SingleMolecule Immunoassay Platform, Small, , 21, - (2025 )
• Structural and dynamic basis of Ssp4mediated DNA protection in foodborne bacterial spores, Scientific Reports, , 15, - (2025 )
• Inferring spatially varying bending stiffness of biopolymers with deeplearning approach, Machine Learning Science and Technology, , 6, - (2025 )
• Singlemolecule visualization of mRNA circularization during translation, Experimental Molecular Medicine, , 55, 283-289 (2023 )
• Formation of cellular closeended tunnelling nanotubes through mechanical deformation, Science Advances, , 8, - (2022 )
• The flipflop configuration of the PABPdimer leads to switching of the translation function, Nucleic Acids Research, , 50, 306-321 (2022 )
• Single polysome analysis of mRNP, Biochemical and Biophysical Research Communications, , 618, 73-78 (2022 )
• Exploiting the distinctive properties of the bacterial and human MutS homolog sliding clamps on mismatched DNA, Journal of Biological Chemistry, , 298, - (2022 )
• Linker domain function predicts pathogenic MLH1 missense variants, Proceedings of the National Academy of Sciences of the United States of America, , 118, - (2021 )
• TRIM28 functions as a negative regulator of aggresome formation, Autophagy, , 17, 4231-4248 (2021 )
• Nonsensemediated mRNA decay factor UPF1 promotes aggresome formation, Nature Communications, , 11, - (2020 )
• DNA Mismatch Repair Relies Entirely on Stochastic Transactions, Biophysical Journal, , 116, 73A-74A (2019 )
• Muts Homolog Sliding Clamps Shield the DNA from Binding Proteins, BIOPHYSICAL JOURNAL, , 116, 75A-75A (2019 )
• Multiplexed singlemolecule flowstretching bead assay for DNA enzymology, BMB REPORTS, , 52, 589-594 (2019 )
• Singlemolecule DNA flowstretching force spectroscopy with higher resolution using darkfield microscopy, Journal of the Korean Physical Society, , 75, 350-354 (2019 )
• DNA skybridge 3D structure producing a light sheet for highthroughput singlemolecule imaging, Nucleic Acids Research, , 47, e107- (2019 )
• MutL sliding clamps coordinate exonucleaseindependent Escherichia coli mismatch repair, Nature Communications, , 10, - (2019 )
• Dynamics of Proofreading by the E coli Pol III Replicase, Cell Chemical Biology, , 25, 57-66 (2018 )
• MutS homolog sliding clamps shield the DNA from binding proteins, JOURNAL OF BIOLOGICAL CHEMISTRY, , 293, 14285-14294 (2018 )
• Coordinating MultiProtein Mismatch Repair by Managing Diffusion Mechanics on the DNA, JOURNAL OF MOLECULAR BIOLOGY, , 430, 4469-4480 (2018 )
• Stochastic Processes and Component Plasticity Governing DNA Mismatch Repair, JOURNAL OF MOLECULAR BIOLOGY, , 430, 4456-4468 (2018 )
• The bent conformation of poly(A)binding protein induced by RNAbinding is required for its translational activation function, RNA biology, , 14, 370-377 (2017 )
• Extended depth of field for single biomolecule optical imagingforce spectroscopy, OPTICS EXPRESS, , 25, 32189-32197 (2017 )
• LightInduced Fluorescence Modulation of Quantum DotCrystal Violet Conjugates Stochastic Off–On–Off Cycles for Multicolor Patterning and SuperResolution, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, , 139, 7603-7615 (2017 )
• Dynamic control of strand excision during human DNA mismatch repair, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 113, 3281-3286 (2016 )
• Pairwise detection of sitespecific receptor phosphorylations using singlemolecule blotting, Nature communications, , 7, 11107- (2016 )
• Retroviral intasomes search for a target DNA by 1D diffusion which rarely results in integration, Nature communications, , 7, - (2016 )
• Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair, NATURE, , 539, 583-+ (2016 )
• Analysis of Interactions between the Epidermal Growth Factor Receptor and Soluble Ligands on the Basis of SingleMolecule Diffusivity in the Membrane of Living Cells, ANGEWANDTE CHEMIEINTERNATIONAL EDITION, , 54, 7028-7032 (2015 )
• An Efficient SiteSpecific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore, SCIENTIFIC REPORTS, , 5, - (2015 )
• Widespread nuclease contamination in commonly used oxygenscavenging systems, NATURE METHODS, , 12, 901-902 (2015 )
• Interplay MutS with beta Clamp on Mismatched DNA, BIOPHYSICAL JOURNAL, , 108, 69A-69A (2015 )
• Poly(A) RNA and Paip2 act as allosteric regulators of poly(A)binding protein, NUCLEIC ACIDS RESEARCH, , 42, 2697-2707 (2014 )
• Aptamerbased singlemolecule imaging of insulin receptors in living cells, JOURNAL OF BIOMEDICAL OPTICS, , 19, - (2014 )
• Loading Dynamics of a sliding DNA clamp, ANGEWANDTE CHEMIEINTERNATIONAL EDITION, , 53, 6768-6771 (2014 )
• Singlemolecule views of MutS on mismatched DNA, DNA REPAIR, , 20, 82-93 (2014 )
• Crystal structures of the structureselective nuclease Mus81Eme1 bound to flap DNA substrates, EMBO JOURNAL, , 33, 1061-1072 (2014 )
• Mapping of Surfaceimmobilized DNA with Forcebased Atomic Force Microscopy, ANALYTICAL CHEMISTRY, , 85, 4045-4050 (2013 )
• PolarizationControlled Photoswitching Resolves Dipole Directions with Subwavelength Resolution, physical review letters, , 109, - (2012 )
• Assessment of radiation damage in singleshot coherent diffraction of DNA molecules by an extremeultraviolet freeelectron laser, Physical review E, , 86, - (2012 )
• ATP Alters the Diffusion Mechanics of MutS on Mismatched DNA, Structure, , 20, 1264-1274 (2012 )
• Unique Temperature Dependence and Blinking Behavior of CdTeCdSe (CoreShell) TypeII Quantum Dots, JOURNAL OF PHYSICAL CHEMISTRY C, , 115, 436-442 (2011 )
• MutS switches between two fundamentally distinct clamps during mismatch repair, NATURE STRUCTURAL AND MOLECULAR BIOLOGY, , 18, 379-U174 (2011 )
• SingleMolecule Analysis Reveals the Kinetics and Physiological Relevance of MutLssDNA Binding, PLOS ONE, , 5, - (2010 )
• Dynamic DNA helicaseDNA polymerase interactions assure processive replication fork movement, MOLECULAR CELL, , 27, 539-549 (2007 )
• DYNAMICS OF THE MOLECULAR ORIENTATION FIELD COUPLED TO IONS IN TWODIMENSIONAL FERROELECTRIC LIQUID CRYSTALS, PHYSICAL REVIEW E, , 76, - (2007 )
• Role of electrostatics in the texture of islands in freestanding ferroelectric liquid crystal films, PHYSICAL REVIEW E, , 75, - (2007 )
• DNA primase acts as a molecular brake in DNA replication, NATURE, , 439, 621-624 (2006 )
• TEXTURAL TRANSFORMATIONS IN ISLANDS ON FREE STANDING SMECTICC LIQUID CRYSTAL FILMS, PHYSICAL REVIEW E, , 73, - (2006 )
• Equilibrium size and textures of islands in free standing Smectic C films, MOLECULAR CRYSTALS AND LIQUID CRYSTALS, , 364, 123-131 (2001 )
• Effect of the external twist on molecular orientation in antiferroelectric liquid crystals, MOLECULAR CRYSTALS AND LIQUID CRYSTALS SCIENCE AND TECHNOLOGY SECTION AMOLECULAR CRYSTALS AND LIQUID CRYSTALS, , 301, 209- (1997 )

학회발표

• Deeplearningbased inference of positiondependent bending stiffness in biopolymers, , , 0, - (2025)
• Novel burstlike cargo transport through tunneling nanotubes, , , 0, - (2025)
• Controlled intercellular transport via Tunneling Nanotubes, , , 0, - (2025)
• A diffusionstate analysis framework for investigating the diffusion dynamics of proteins, , , 0, - (2025)
• Single mRNA Translation Imaging in Cells, , , 0, - (2025)
• Novel cargo transport via intercellular nanotubes, , , 0, - (2025)
• Statistical physicsinformed analysis of fluctuations across scales from living to astrophyical systems, , , 0, - (2025)
• A diffusionstate analysis framework for investigating the diffusion dynamics of proteins, , , 0, - (2025)
• 1DDiffusion dynamics of human PCNA protein on DNA insights from sinhlemolecule tracking trajectory data, , , 0, - (2025)
• smDeepFLUOR SINGLEMOLECULE DEEP LEARNING FLUORESCENCE CLASSIFICATION, , , 0, - (2025)
• DNA sky bridge combined Flow stretching bead assay, , , 0, - (2025)
• Single mRNA Translation Imaging in Cells, , , 0, - (2024)
• DNA sky bridge combined Flow stretching bead assay, , , 0, - (2024)
• deepFLUOR Deep Learning Classification of SingleMolecule Signals, , , 0, - (2024)
• deepFLUOR Deep Learning based SingleMolecule Images Classification , , , 0, - (2024)
• Visualization of intercellular cargo transport via tunneling nanotube, , , 0, - (2024)
• Singlemolecule imaging platforms for singleparticle tracking singlemolecule blotting, , , 0, - (2023)
• Formation Mechanism of Tunneling Nanotubes, , , 0, - (2023)
• Discovering new diffusion states of MutS homologs from singlemolecule trajectories via hidden Markov models, , , 0, - (2023)
• Identification of a new diffusion state of MSH2MSH6 sliding clamp via hidden Markov models, , , 0, - (2022)
• Identification of unpredicted onedimensional diffusion states of MutS via hidden Markov models, , , 0, - (2022)
• Single polysome analysis of mRNP, , , 0, - (2022)
• Formation of Cellular Closeended Tunneling Nanotubes through Mechanical Deformation, , , 0, - (2022)
• THE FORMATION OF FILOPODIA BRIDGE AND INTERCELLULAR NANOTUBE A CRITICAL RULE OF TORQUE AND RESTORATIVE FORCE, , , 0, - (2022)
• DNA mismatch removal and resynthesis by Polymerase delta , , , 0, - (2022)
• Novel surfacefreemultiplexed singlemolecule blotting platform , , , 0, - (2022)
• Semiin vivo stoichiometry study of initiation factors in mRNA during translation, , , 0, - (2022)
• A coarsegrained model and simulation study on intercellular nanotube formation from two filopodia, , , 0, - (2021)
• How the filopodia make intercellular nanotube the effects of torque and restorative force, , , 0, - (2020)
• Singlemolecule imaging of PAF15PCNA using DNA skybridge, Biophysical Journal, , 0, - (2020)
• Direct connection of distant cells by filopodial bridges, , , 0, - (2020)
• Direct connection of distant cells by filopodial bridges, , , 0, - (2020)
• Singlemolecule imaging of translation initiation in live cells , POSTECHAPCTP Meeting, , 0, - (2020)
• Formation of Intercellular Nanotubes via Helical Deformation, POSTECHAPCTP Meeting, , 0, - (2020)
• Singlemolecule fluorescence imaging of MLH endonuclease, POSTECHAPCTP Meeting, , 0, - (2020)
• Mismatch recognition and removal in human cell extracts, POSTECHAPCTP Meeting, , 0, - (2020)
• Langevin dynamics simulation of the mechanism of the intercellular nanotube, 2019 International Conference on Molecular Simulation, , 0, - (2019)
• How Cells Kiss, Statistical Physics for Biological Matter, , 0, - (2018)
• Langevin dynamics simulation on the two interwound filopodia in the process of intercellular nanotube formation, 2018년 추계 한국물리학회, , 0, - (2018)
• Twisting of filopodia stiffens filopodial bridges for intercellular nanotube formation, 2018년 추계 한국물리학회, , 0, - (2018)
• Formation mechanics of intercellular nanotubes, 2018 GOEDON RESEARCH CONFERENCE, , 0, - (2018)
• Dynamics of Proofreading by EColi Pol III Replicase, 10th BK21 Young Physicists Workshop, , 0, - (2018)
• Alternative structures of PABP determine functions of the protein by changing interacting partners, , , 0, - (2017)
• SingleMolecule Approaches to Membrane Nanotubes, , , 0, - (2016)
• Interplay MutS with β clamp on Mismatched DNA, , , 0, - (2015)
• Singlemolecule Study on the Proofreading activity of DNA Polymerase III, , , 0, - (2014)
• Removal Process of Mismatched Nucleotides during DNA Mismatch Repair, , , 0, - (2014)
• Diffusion Mechanics of the MutS and β clamp complex on Mismatched DNA, , , 0, - (2014)
• Loading Dynamics of DNA Replication Slidingclamp, , , 0, - (2014)
• Single Molecule Studies on the Human DNA Mismatch Removal, , , 0, - (2013)
• Visualizing Conformational Changes and Diffusion Dynamics of DNA Replication Holoenzyme Betasliding clamp, , , 0, - (2013)
• ATP Alters the Diffusion Mechanics of MutS on Mismatched DNA, , , 0, - (2012)
• Superresolution and molecular orientation achieved by polarizationrotating TIRF microscopy, , , 0, - (2012)
• Dynamics of the Signaling MutS during Mismatch Repair, , , 0, - (2012)
• Poly(A) Binding Protein Tightly Bound to Poly(A) Its bent conformation and Dissociation Mechanism by Paip2, , , 0, - (2012)
• A simple flowstretching method for a higher spatial resolution, , , 0, - (2011)
• Orientation and Rotational Diffusion of MutS during mismatch Repair, , , 0, - (2011)
• SINGLEMOLECULE STUDY OF HUMAN POLY(A)BINDING, , , 0, - (2011)
• DISTINCT CONFORMATIONAL CHANGES OF MUTS DURING, , , 0, - (2011)
• Direct observation of the dynamics of Taq MutS on mismatched DNA, , , 0, - (2010)
• Realtime Observation of Cytokine Signaling Proteins in Living Cells, , , 0, - (2009)
• DNA mismatch repair at the singlemolecule level, , , 0, - (2009)